Zum Inhalt springen
Sponsorship
Die MVF-Knowledge-HubsFrisch aus der Forschung. Täglich aktualisiert!

Suchen Sie in Hunderten nationaler und internationaler Datenbanken nach dem neuesten Studienwissen der angegebenen Themengebiete und/oder lassen Sie sich werktäglich per Newsletter informieren. Die Newsfeeds werden auf deutsch übersetzt and nach Übertragbarkeit auf das deutsche Gesundheits-/Versorgungssystem ausgewählt:

Zu den Knowledge-Hubs

Abstracts by keywords: dementia

Zusammenhang zwischen einer Therapie mit SGLT2-Inhibitoren und Demenz bei älteren Erwachsenen mit Typ-2-Diabetes

Demenz stellt eine wachsende globale Herausforderung für die öffentliche Gesundheit dar; die Zahl der Betroffenen wird bis 2030 auf 78 Millionen geschätzt. Mit der steigenden Lebenserwartung nimmt auch die sozioökonomische und gesundheitliche Belastung durch Demenz erheblich zu. Der Typ-2-Diabetes mellitus (T2DM) ist ein gut etablierter Risikofaktor und erhöht die Wahrscheinlichkeit, eine Demenz – einschließlich Alzheimer-Krankheit und vaskulärer Demenz – zu entwickeln, um bis zu 60% [Biessels & Despa, 2018]. Die pathophysiologischen Mechanismen, die T2DM mit Demenz verbinden, umfassen chronische Hyperglykämie, Insulinresis-tenz, zerebrovaskuläre Dysfunktion, Neuroinflammation und oxidativen Stress – alles Faktoren, die zum kognitiven Abbau beitragen [Beeri & Bendlin, 2020]. Trotz intensiver Forschung existieren bislang keine krankheitsmodifizierenden Therapien für Demenz, was die Notwendigkeit unterstreicht, modifizierbare Risikofaktoren sowie pharmakologische Strategien zur Verlangsamung des kognitiven Abbaus zu identifizieren [Livingston et al., 2020].

30.11.2025
Care situation of swallowing disorders in nursing homes – challenges and needs

Healthy people swallow up to 2,000 times a day without even thinking about it. Aging processes jeopardize the adequacy of swallowing: Swallowing disorders in nursing homes are underdiagnosed, their impact underestimated, yet, along with their complications, they are the most common cause of death there. A closer look reveals a devastating picture of care. This paper outlines the current challenges of data inaccuracy and the lack of diagnostic and therapeutic care against the backdrop of possible innovative forms of care and their implementation in a care pathway yet to be developed.

03.12.2024
Hospital mortality in patients with and without dementia

Previous studies have reported increased in-hospital mortality in patients with dementia (PwD), but findings across age groups, clinical departments, and admission diagnoses have been limited. The aim of this study is to compare in-hospital mortality in PwD across age groups, clinical departments, and admission diagnoses with that of control subjects without dementia.

03.12.2024
Symptoms of early Alzheimer's disease and new treatment options

At the beginning of 2020, the "Interdisciplinary discussion forum on ethical, economic and medical challenges before the onset of dementia" was established in order to establish the public discussion on fundamental topics regarding diagnostics, therapy and care of dementia patients, which show a concrete need for action. found together. Current developments in the therapeutic field are discussed as well as ethical problems, gaps in care and special topics such as the use of biomarkers for risk stratification of patients in the early diagnosis of Alzheimer's disease.

05.06.2023
logo The invisible people responsible: relatives in reporting on dementia

Dementia is a challenge for society as a whole, and nursing care in particular is a major task. People with dementia are often cared for at home, the professional care situation in Germany is tense - relatives are often involved in the care themselves or care for them alone, which means a high level of physical and psychological stress.

04.02.2023
Well-being of people with dementia through lived spirituality - an exploratory study

The increasing aging of society has led to an increase in age-related diseases in recent years. This particularly includes dementia. The term comes from Latin and describes the absence (prefix: de-) of the ability to think (suffix: -mens). “Dementia” literally means “without reason”. Dementia is not only accompanied by cognitive and mnestic losses, but also by the loss of basic orientation and everyday skills that were previously taken for granted (Stoffers 2016: 7). The term dementia does not include a specific disease, but rather an acquired condition caused by organic brain damage (Stoffers 2016: 8). In Germany, there are currently around 1.7 million people living with a diagnosis of dementia (Thyrian et al. 2020: n.p.), with Alzheimer's dementia making up the majority of the diseases with around 60% (Stoffers 2016: 9). So far there is little knowledge regarding the triggering risk factors, but different expert assessments and study notes show (at different levels of evidence) that different prevention approaches could be useful for avoiding dementia. These include, among other things, increasing exercise behavior, quitting smoking, or reducing alcohol consumption (WHO 2019: xii-xiii). Social contacts as well as intensive cultural and sporting activity also appear to be protective factors against the development of dementia (Förstl, Förstl 2020: n.p.).

23.03.2022
Care for patients with dementia before and after initial diagnosis

The diagnosis of dementia is an enormous emotional and financial burden for many of those affected and their relatives. At the same time, it represents a major cultural and political challenge for society. There are no treatment options. It is therefore important for everyone involved to learn to live with dementia and to find ways that enable them to live a good life despite the illness (cf. Klie 2017). Dementia is the most common “mental” illness in older people and one of the most common reasons for the need for care. The most common forms of dementia are Alzheimer's disease (ICD codes F00. & G30.) and vascular dementia (ICD F01.), which is caused by damage to the blood vessels in the brain. There are also secondary forms of dementia (F02.), e.g. B. in connection with Parkinson's or HIV, and unspecified forms of dementia (F04.). These five ICD codes were used in the analysis to identify patients with dementia and a level of care.

04.06.2018
Hip fracture risk in dementia patients in German general practices

Dementia is a psychiatric disease caused by neurodegeneration, characterized by a progressive loss of cognitive functions, leading to changes in patients' daily lives (WHO, 2015). 47.5 million people worldwide suffer from dementia, and this number is expected to rise to 75.6 million by 2030 and exceed 140 million by 2050 (WHO, 2015). In Germany, dementia affects around 1.2 million people, mainly women and seniors. Approximately 200,000 new cases are diagnosed every year (Tunstall, 2015). The average cost associated with these mental illnesses is more than 43,000 euros per patient per year, with almost 68% of this amount borne by carers and families (Tunstall, 2015). Dementia therefore has a significant impact on patients and their relatives, which underlines the need for specially adapted treatments and appropriate management of the disease in Germany.

31.03.2016
Dementia diseases between medicine and nursing – difficulties for health services research

Using the example of dementia-related illnesses, the Barmer-GEK Care Report 2010 implicitly shows an essential dilemma in health services research: On the one hand, the diverse interdependencies between care and dementia are very well illuminated, and on the other hand, the broader connections between medicine, care and dementia can be presented, but on the other hand The presentation is only of limited use because billing data from outpatient and statutory health care is becoming less and less useful for making statements about the quality of care. This is becoming an increasing challenge for health insurance companies and the health system: How can the performance data from outpatient and statutory health care be meaningfully used for health services research?

23.09.2012
Outpatient residential communities for people with dementia – a form of care with a future?

Like many others - especially Western countries - the demographic age structure of the Federal Republic of Germany will change significantly in the next few years. According to the Federal Statistical Office (2006: 23), the number of people aged 65 to under 80 will increase from 12 million in 2005 to 13 million in 2050. At the same time, the number of older and very old people in society will also increase of people in need of care. This means that the question of supply requirements and needs is increasingly coming to the fore. Particular attention must be paid to the care of people with dementia (PwD), since dementia-related diseases are among the most serious and numerically most common diseases in old age and the prevalence of dementia-related diseases increases significantly with increasing age (Weyerer 2005: 7). It is currently estimated that there will be more than two million people with dementia in Germany by the year 2050 (Ziegler/Doblhammer 2009; German Alzheimer Society 2008; Bickel 2001; Bickel 2000). According to a press release from the Federal Statistical Office, the medical costs for dementia in Germany in 2008 were estimated at 9.4 billion euros. “In the case of dementia and depression alone, the costs increased during this period [from 2002 to 2008] by a total of 3.5 billion euros or 32 billion euros. Overall, medical costs have increased by 35.5 billion euros since 2002 (+ 16 %) and amounted to 254.3 billion euros in 2008.” (Federal Statistical Office 2010).

24.02.2012

Do you want to leave us already?

Subscribe to our newsletter quickly. Then you can be sure that you won't miss anything.