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Disease interception

Detecting and stopping diseases before they break out is a fascinating idea. Disease Interception aims to do just that. The concept envisages diagnosing and treating those affected much earlier than today - before clinical symptoms appear - and interrupting the disease process in the preclinical stage. Disease Interception would mean a paradigm shift for those affected, their relatives, doctors and the healthcare system as a whole. This brings with it questions that extend far beyond medicine, including social, regulatory, legal and ethical issues. In order to answer them, a discourse between all actors is required. The publication “Disease Interception”, supported by Janssen Germany, makes a contribution to this. The editors, Prof. Dr. med. Frank Jessen and Dr. med. Christoph Bug, have invited well-known experts from medicine, research, health industry and society to evaluate the concept of disease interception: D. Berron | F. von Bohlen and Halbach | C. Bug | M. Danner | E. Düzel | M. Hennrich | W. Hoffmann | F. Jessen | F. Knieps | P. Langkafel | J.-M. Löhr | D. Matusiewicz | S. Maul | M.-S. Raab | H. Rebscher | R. Roski | D. Rujescu | C. Stallberg | A. Ullmann | J. Wasem | J. Werner | J. Wiltfang | E. Winkler | I. Zwingmann

Table of contents

New in the Monitor Health Services Research series: Disease Interception. Here you will find author information with links to the respective articles and interviews.

Preface

Prof. Dr. med. Frank Jessen

Disease Interception – great opportunities and such
Challenges for future medicine

Citation: Jessen, F.: “Disease Interception – great opportunities and challenges for the medicine of the future”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 5-10

Editorial

Prof. Dr. Reinhold Roski

Bold Hope: Disease Interception

Citation: Roski, R.: “Bold Hope: Disease Interception”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 11-14

Dr. Martin Danner

The paradigm of disease interception from the patient's perspective

Citation: Danner, M.: “The paradigm of disease interception from the patient’s perspective”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 17-26

Prof. Dr. med. Dr. phil. Eva Winkler

Ethical considerations for disease interception

Citation: Winkler, E.: “Ethical considerations for disease interception”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 27-38

Prof. Dr. med. Jochen A. Werner

Thoughts on the doctor-patient relationship in the context of disease interception

Citation: Werner, J.: “Thoughts on the doctor-patient relationship in the context of disease interception”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 39-47

marc-steffen-raab

Prof. Dr. med. Marc Steffen Raab

Opportunities for disease interception in oncology

Citation: Raab, M.-S.: “Chances of Disease Interception in Oncology”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 51-59

Prof. Dr. med. Dan Rujescu,
Dr. med. Stephen Maul

Perspectives on Alzheimer's therapy

Citation: Rujescu, D., Maul, S.: “Perspectives on Alzheimer’s therapy”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 61-67

jens-wiltfang

Prof. Dr. med. Jens Wiltfang

Blood-based diagnostics of preclinical Alzheimer's dementia: recruitment aid for clinical studies on disease interception in Alzheimer's disease

Citation: Wiltfang, J.: “Blood-based diagnostics of preclinical Alzheimer’s dementia: recruitment aid for clinical studies on disease interception in Alzheimer’s disease”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 69-78

Dr. David Berron,
Prof. Dr. med. Emrah Düzel

Digital monitoring of specific cognitive impairments in early Alzheimer's disease

Citation: Berron, D., Düzel, E.: “Digital monitoring of specific cognitive impairments in early Alzheimer’s disease”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 79-91

Dr. Friedrich von Bohlen and Halbach,
Prof. Dr. Johannes-Matthias Löhr

Disease Interception – Oncology & Genetics: Evidence-based interception for prevention and therapy

Citation: von Bohlen und Halbach, F., Löhr, J.-M.: “Disease Interception – Oncology & Genetics: Evidence-based Interception for Prevention and Therapy”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 93-100

peter-langkafel

Dr. med. Peter Langkafel

Is data the stethoscope of the 21st century?

Citation: Langkafel, P.: “Are data the stethoscope of the 21st century?”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 101-116

Prof. Dr. med. Wolfgang Hoffmann,
Dr. med. Stephen Maul

Opportunities and challenges of disease interception for dementia diseases from the perspective of health services research

Citation: Hoffmann, W,. Zwingmann, I.: “Opportunities and challenges of disease interception for dementia diseases from the perspective of health services research”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 119-132

Prof. Dr. David Matusiewicz

Consideration of disease interception from a health economics perspective

Citation: Matusiewicz, D.: “Consideration of disease interception from a health economics perspective”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 133-145

Prof. Dr. David Matusiewicz

Disease Interception: More than a therapeutic and systemic innovation – a paradigm shift for our healthcare system

Citation: Wasem, J.: “Disease Interception: More than a therapeutic and systemic innovation – a paradigm shift for our healthcare system”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 147-155

Michael Hennrich, MP

“Given that the prevalence of Alzheimer’s disease will triple worldwide by 2050, we cannot turn a blind eye to an opportunity like Disease Interception.”

Citation: Hennrich, M., Stegmaier, P.: “If we assume that the prevalence of Alzheimer's disease will triple worldwide by 2050, we cannot close our eyes to an opportunity like Disease Interception”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 159-166

Prof. Dr. Andrew Ullmann, MP

“Disease interception offers the chance that diseases that occur particularly in old age, such as dementia, cancer or cardiovascular diseases, could be conquered in the future”

Citation: Ullmann, A.: “Disease interception offers the chance that diseases that occur particularly in old age, such as dementia, cancer or cardiovascular diseases, could be conquerable in the future”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 167-170

Franz Knieps

“The health system must focus less on curative activity and more on prevention”

Citation: Knieps, F., Stegmaier, P.: “The health system must focus less on curative activity and more on prevention”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 171-183

Prof. Dr. hc Herbert Rebscher

“Disease Interception: Potential for harm and benefit remain the measure of all things”

Citation: Rebscher, H., Stegmaier, P.: “Disease Interception: Potential for harm and benefit remain the measure of all things”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 185-197

Dr. Christian Stallberg, LL.M.

Disease Interception as a benefit of statutory health insurance? – Legal challenges and perspectives

Citation: Stallberg, C.: “Disease Interception as a benefit of statutory health insurance? – Legal challenges and perspectives”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 199-215

Dr. med. Christoph Bug

Disease Interception: Making the vision a reality

Citation: Bug, C.: “Disease Interception: Making the Vision a Reality”; in Jessen, F., Bug, C. (eds.): “Disease Interception”, eRelation Verlag, Bonn, 2019, pp. 219-222

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