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Abstracts by keywords: Covid-19

Increase in upper respiratory tract infections following the Covid-19 pandemic

In dieser Querschnittsstudie wurde die Anzahl der Patienten mit einer Diagnose von Infektionen der oberen Atemwege (= Upper Respiratory Tract Infections, URTI) und mit Antibiotikaverordnungen aus der Disease Analyzer Datenbank (IQVIA) zwischen Januar 2019 und Dezember 2022 ausgewertet. Die Anzahl der Patienten mit URTI-Diagnosen und Antibiotikaverordnungen pro Praxis sowie die Dauer der Krankschreibung pro Patienten wurden im Zeitverlauf verglichen. Insgesamt wurden 1.403.907 Patienten aus Hausarztarztpraxen eingeschlossen, von denen 48% weiblich waren. Die Anzahl der URTI-Patienten pro Praxis war im Jahr 2022 signifikant höher als im Jahr 2019 (732 vs. 464, 58%, p<0,001), und dies sowohl bei Frauen (56%, p<0,001) als auch bei Männern (60%, p<0,001). Der Anstieg der Anzahl der URTI-Diagnosen nach der Pandemie korrelierte mit dem Alter und war am höchsten in der Altersgruppe zwischen 18 und 30 Jahren (22%, p<0,001) und am niedrigsten bei älteren Patienten über 70 Jahren (3%). Sowohl die Anzahl der Patienten pro Praxis, die aufgrund von URTI krankgeschrieben wurden (184 vs. 92), als auch die durchschnittliche Dauer der Krankschreibung (+2 Tage) nahmen von 2019 bis 2022 zu. Unsere Daten deuten auf einen dramatischen Anstieg der Inzidenz von URTI in allen demografischen Untergruppen in Deutschland zwischen 2019 und 2022 hin, der mit einem enormen Einfluss auf sozioökonomische Variablen wie die Häufigkeit oder Dauer von Krankschreibungen verbunden war. Diese Daten könnten für das aktuelle Pandemiemanagement und das Management zukünftiger Pandemien von großer Bedeutung sein.

02.02.2024
Mysterious data politics

Mysterious Data Policy >> In the social sciences, the inadequate coronavirus data policy of the Robert Koch Institute (RKI) and its focus on the daily or cumulative number of confirmed COVID-19 cases were criticized, albeit only sporadically, as early as spring 2020. For example, one of Germany's leading sociologists, Rainer Schnell—together with Menno Smid of the Infas Institute […]

02.08.2023
The importance of technical and scientific basic principles and the consequences of their disregard

The statements of the thesis paper author group between April 2020 and June 2022 covered three levels: the infection epidemiological situation as a basis, the modern, multimodal prevention concepts as an option for action and the societal level as a context that must be taken into account. Numerous other groups and individuals have set comparable priorities, but overall the reversal of central professional standards in health care with regard to infection management could not be prevented, nor could the use of inadequate prevention concepts and the narrowing of social discourse, the incitement of critical opinions and the revival of “governance” .

05.06.2023
The influence of the SARS-CoV-2 pandemic on the work of STIKO and suggestions for preparing for the next pandemic

An analysis of the referrals of the Standing Vaccination Commission (STIKO) with indications/vaccines in the period from January 1, 2015 to June 30, 2022 enables a comparison of the average values of referrals by number and intensity between the pre-pandemic years 2015 to 2019 and the pandemic years 2020 and 2021.

04.02.2023
7. Ad hoc statement on the SARS-CoV-2/Covid-19 pandemic

The 7th ad hoc statement from the theses paper author group deals with the topic of the changed STIKO recommendation of May 25th on vaccination in children. Surprisingly, on May 24th, the Standing Vaccination Commission (STIKO) spoke out in favor of the (single) vaccination of healthy children aged 5 to 11 years with an mRNA vaccine, preferably with “Comirnaty”. However, the studies on which the changed recommendation is based only refer to adults; the scientific justification does not provide any evidence for this age group. Consequently, the STIKO also states that the recommendation is being made as a precautionary measure because a renewed increase in SARS-CoV-2 infections is to be expected next autumn. It remains unclear whether a new variant will emerge at all (probable) and whether the vaccine based on the wild type will help against it (questionable). As of: June 23, 2022, 6:00 p.m

22.07.2022
8. Ad hoc statement: Change of strategy necessary

Covid-19: What is the current infectious situation? Like the rest of Europe and the rest of the world, Germany is currently transitioning into the endemic-epidemic phase of the SARS-CoV-2 pandemic. The currently dominant virus variants (Omicron BA4 and BA5) are characterized by a very high level of contagiousness and, at the same time, a very low disease burden. Even among the very elderly residents of nursing homes, who are considered particularly vulnerable, the severity of the disease and the hospitalization rate decreased significantly under the Omicron variant and after the vaccination campaign; mortality compared to 2020 even increased by more than 90%. The currently dominant variants have led to a significant increase in infections among those vaccinated and those who have recovered, with some clinical signs of a flu-like infection, without this being associated with a noticeable overload on the healthcare system and critical infrastructure. The few cases of overload reported were not a result of increased use of intensive care resources, but rather the consequence of isolation measures for staff that were ordered regardless of any symptoms.

24.06.2022
No increased risk of venous thrombosis and pulmonary embolism after SARS-CoV-2 vaccination in Germany

The Covid-19 pandemic has had a dramatic impact on social life and economic development worldwide (1-5). The use of recently developed vaccines has proven effective in combating the spread of severe acute respiratory syndrome SARS-CoV-2 and preventing severe Covid-19 (6). However, vaccine hesitancy is reported in many countries for various reasons (7). Although vaccine distribution and administration has increased over time, some vaccine hesitancy remains a problem (7, 8). In addition to the obvious differences in vaccination rates between developed and developing countries, a similar trend in vaccine hesitancy emerged, with factors such as higher levels of education, higher income, residence outside of rural areas or the provision of free vaccinations as key factors in acceptance of vaccinations have been identified (7, 8). Some research has found that general trust in authorities and the government is strongly correlated with willingness to be vaccinated (7). However, possible side effects of the vaccine were identified as the most common reason for hesitation about the Covid-19 vaccination and were mentioned by more than 90% of the vaccine opponents surveyed (8, 9). Acute illnesses such as stroke and myocardial infarction were documented less frequently. The behavioral change that resulted from the implementation of strict hygiene rules may also have led to a “real” decrease in the rates of non-Covid-19 infectious diseases (5,6). In other words, the measures taken to combat the Covid-19 pandemic may also have influenced the spread of other germs that cause respiratory tract infections (AI) and gastrointestinal infections (GI). For this reason, in the present study the authors wanted to investigate the frequency of these AI and GI during the Covid-19 pandemic using data from a large database that includes anonymized treatment information from general practitioners and pediatricians in Germany.

23.03.2022
On modeling the corona pandemic - a polemic

Nationally and internationally, mathematical models of the infection process in the corona pandemic have had an enormous political impact. However, the model-heavy nature of the political decision-making processes has also been widely criticized. From both a technical and a sociological perspective, criticism of maneuvers appears to be necessary due to numerous indications. The extent to which the performance of government-related epidemic modeling in particular has met the challenges should be critically questioned and evaluated in wider circles. Model uncertainties and the complexity of the problem of the spread of infectious diseases should be given greater attention. There needs to be a deeper awareness that mathematical models cannot replace practical medical experience and classical concepts for controlling complex systems.

29.11.2021
4. Ad hoc statement on the SARS-CoV-2/Covid-19 pandemic

The thesis paper author group presents its 4th ad hoc statement with twelve concrete demands that should be initiated on the new health minister's first working day. The group of authors is speaking out at a time when the new appointment at the top of the Federal Ministry of Health makes a new beginning seem possible. As of November 28, 2021, 6:00 p.m

29.11.2021
Thesis paper 8.0 on the pandemic caused by SARS-CoV-2/Covid-19

Bei diesem Text handelt es sich um die Kurzfassung, des Thesenpapiers 8.0, das die Autorengruppe (siehe MVF Online First) erarbeitet hat (Datum 29.8.2021), das zu folgenden Aspekten Stellung nimmt:1. Es wird ein Konzept für das Verständnis der Epidemie entwickelt (Kap. 2 „Pandemie als Komplexes System“), mit dem das schwer zu entschlüsselnde Verhalten der Epidemie zu erklären ist, und das es erlaubt, Empfehlungen für die Steuerung (Messparameter) und die Präventionsstrategie abzuleiten;2. Es wird ein Indikatoren-Set entwickelt (Kap. 3), das die Melderate („Inzidenz“) ablösen kann und über eine erheblich bessere Aussagekraft verfügt;3. Es werden in einem umfangreichen, kritischen Ansatz das Wissen zur SARS-CoV2-Epidemie im Kindes- und Jugendalter dargestellt (Kap. 4) und weitgehende Erleichterungen für diese bisher am stärksten psychosozial belastete Bevölkerungsgruppe gefordert;4. Es wird eine Politische Theorie der Pandemie vorgestellt, die die „Massivreaktion“ der gesellschaftlichen und politischen Ebenen erklärt und für die Diskussion der Handlungsoptionen öffnet.Die Autorengruppe beschäftigt sich seit März 2020 ehrenamtlich mit der Corona-Thematik und greift kontinuierlich mit Thesenpapieren und Ad-hoc-Stellungnahmen in die politische Diskussion ein.

22.09.2021

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